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Comparison of Neisseria gonorrhoeae Multiantigen Sequence Typing and porB Sequence Analysis for Identification of Clusters of N. gonorrhoeae Isolates▿ †

机译:淋病奈瑟菌多抗原序列分型和porB序列分析用于鉴定淋病奈瑟菌分离株的比较

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摘要

porB DNA sequence analysis and Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) methods were compared for their abilities to discriminate strains and to identify epidemiologically congruent pairs of N. gonorrhoeae. Both methods provided high-level discrimination of strains. NG-MAST further differentiated large porB-based clusters. However, considerations of cost suggest that porB DNA sequence analysis is a useful tool for preliminary molecular analysis of the epidemiology of N. gonorrhoeae.
机译:比较了porB DNA序列分析和淋病奈瑟氏球菌多抗原序列分型(NG-MAST)方法,以区分菌株和鉴定流行病学上一致的淋病奈瑟氏菌对。两种方法都可以对菌株进行高级区分。 NG-MAST进一步区分了基于porB的大型集群。但是,出于成本考虑,porB DNA序列分析是淋病奈瑟菌流行病学初步分子分析的有用工具。

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